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However, most of them are not in clinical trials yet and not much is known about their advantage in a head to head comparison to established gliptins

Conclusion Beyond their established role as potent antihyperglycemic agents, GLP-1RAs show potential for treating neurodegenerative diseases with disease-modifying effects

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Disease progression in both trials was assessed using the Clinical Dementia Rating Sum of Boxes (CDR-SB) score, a widely used measure of cognitive and functional decline in AD clinical trials